Principal Investigator: Anuja Jhingran, MD
Primary Objective:
To determine if adjuvant systemic chemotherapy following chemoradiation therapy will improve disease-free survival compared to chemoradiation therapy alone in patients with high-risk earlystage cervical carcinoma found to have positive nodes and/or positive parametria after a radical hysterectomy.
Patient Population:
To determine if adjuvant systemic chemotherapy following chemoradiation therapy will improve disease-free survival compared to chemoradiation therapy alone in patients with high-risk earlystage cervical carcinoma found to have positive nodes and/or positive parametria after a radical hysterectomy.
Patient Population:
Patients with clinical stage IA2, IB or IIA squamous, adenosquamous, or adenocarcinoma of the cervix who have any/all of the following high-risk features after surgery (this corresponds to surgical TNM staging of T1-T2, N1, M0):
